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The U.S. Public Health Service · Episode 32 of 34 · 30 min

Mumps: The Vaccine From a Child's Throat (1963–2026)

In 1963 vaccine scientist Maurice Hilleman cultured mumps virus from the throat of his own sick five-year-old daughter, Jeryl Lynn, and built a vaccine that still bears her name and nearly erased a leading cause of childhood deafness. The humbling lesson came later, when mumps surged back among young adults who had received both doses, showing that immunity fades. The CDC's advisers recommended a third dose for people at high risk during outbreaks.

Who's who

  • Maurice HillemanMerck vaccine scientist who developed the mumps vaccine from his daughter's infection

Timeline

  1. 1963Hilleman cultures mumps virus from his daughter's throat
  2. 1967Mumps vaccine (Jeryl Lynn strain) licensed
  3. 1971Mumps vaccine combined into MMR
  4. 2006Large Midwest college outbreak among two-dose-vaccinated students
  5. 2016-2017Renewed large outbreaks, heavily on college campuses
  6. 2017-2018Advisers recommend a third MMR dose for those at risk during outbreaks

Still debated

The evidence points to waning immunity rather than vaccine failure or a mutating virus. The third dose is recommended only for people at increased risk during an outbreak, and mumps was never declared eliminated in the U.S.

mumpsmmr vaccinemaurice hillemanwaning immunityoutbreakscollege campuses
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