Chlamydia is the most commonly reported infection in America, with well over a million and a half cases a year, and most cause no symptoms. Untreated, it quietly scars the reproductive tract. The cure was never the problem; finding it was, until 1990s nucleic-acid tests allowed detection from a urine sample and made mass screening of young women possible.
Estimates of the symptomless share vary by study, and some rise in reported cases reflects better testing rather than more infection. Routine screening of young men is less clearly established than for women.