Ferdinand de Lesseps, hero of Suez, took on Panama in 1880 and insisted on a sea-level canal. Disease killed about 22,000 workers, and the 1889 financial collapse ruined 800,000 small investors. The ensuing Panama Scandal brought prosecutions and an antisemitic backlash in France.
The accepted toll is about 22,000 dead, though the company suppressed records. Eiffel was convicted but the verdict was later annulled, and his exact responsibility is debated. The scandal gravely discredited the political class and fed antisemitic movements.